Alterations in gastrointestinal physiology after Roux-en-Y gastric bypass.

نویسندگان

  • Todd A Ponsky
  • Fredrick Brody
  • Edward Pucci
چکیده

m h a r orbid obesity is increasing exponentially in the US. pproximately 33.3% of Americans were obese in 1991, ersus 25.4% in 1976. Currently, 54.5% of Americans re overweight, with a body mass index 25. Diet and xercise are implemented initially, they usually fail after years. In response to this epidemic, surgical therapies or morbid obesity have evolved. There are several diferent weight loss operations available, including Rouxn-Y gastric bypass (RYGB), biliopancreatic diversion, uodenal switch, vertical banded gastroplasty, and the apBand. The most common procedure performed in he US is RYGB, which is both a restrictive and malaborptive operation. Although there are several variations vailable for RYGB, the general principles are similar. he first part of the operation creates a gastric pouch of pproximately 20 cm to restrict oral intake. The second omponent of the operation involves construction of a iliopancreatic limb that diverts bile and pancreatic luid from the proximal to the distal small intestine. This istal diversion creates a segment of small bowel that llows food to pass without interacting with bile or panreatic fluid. This diversion delays the interaction of ancreatic enzymes and biliary secretions with the food olus. Finally, this bypass effectively alters normal nutrint exposure to the duodenum. Although this procedure can alter normal physiology, t has the propensity to increase survival for morbidly bese patients. A recent study by Patterson and coleagues suggests that life expectancy improves by almost 1% after laparoscopic RYGB, compared with diet and xercise alone. Flum and Dellinger found that morbidly bese patients had a 33% decreased hazard of death after astric bypass.

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عنوان ژورنال:
  • Journal of the American College of Surgeons

دوره 201 1  شماره 

صفحات  -

تاریخ انتشار 2005